Infant Resuscitation

Respiratory Distress Syndrome in Newborns: Causes and Initial Management

Transient tachypnea, meconium aspiration, and surfactant deficiency – how healthcare professionals and parents can distinguish the most common causes of neonatal respiratory distress and which immediate measures can be lifesaving.

Dr. med. univ. Daniel Pehböck, DESA

Author: Dr. med. univ. Daniel Pehböck, DESA

Specialist in Anesthesiology and Intensive Care Medicine, AHA-certified ACLS/PALS Instructor, Course Director Simulation Tirol

Reading time approx. 10 min

When a newborn can't breathe properly after birth, it's a moment of extreme tension for everyone involved. Respiratory distress is one of the most common complications in the first hours and days of life – and it can have many different causes. Some resolve on their own, while others require swift, decisive action. As a parent, grandparent, or caregiver, it's incredibly valuable to understand why a baby might develop breathing problems, how to recognize the warning signs, and what you can do in an emergency until professional help takes over. This article explains the three most common causes of neonatal respiratory distress in plain language and shows you which initial measures can truly be lifesaving.

Why Breathing Is Such a Huge Challenge for Newborns

To understand why newborns can develop breathing problems at all, it helps to take a brief look at what happens in the body during birth. In the womb, the baby's lungs are filled with amniotic fluid. The baby doesn't receive oxygen through its own breathing but through the umbilical cord and the placenta. With the first breath after birth, everything must change in a split second:

  • The lungs must expand and displace the amniotic fluid.
  • The tiny air sacs (alveoli) must fill with air and stay open.
  • The circulatory system must completely switch over – away from the placenta and toward the baby's own lungs.

This transition is one of the most dramatic adaptations the human body ever accomplishes. In the vast majority of cases, it goes smoothly. But sometimes there are disruptions – and then the baby needs support.

The Three Most Common Causes of Neonatal Respiratory Distress

Transient Tachypnea – the "Wet Lung"

What happens?

Transient tachypnea (the name sounds complicated but simply means "temporarily fast breathing") is the most common and generally the most harmless form of respiratory distress in newborns. It occurs when the amniotic fluid isn't absorbed from the lungs quickly enough after birth. Normally, a large portion of this fluid is squeezed out of the lungs by the pressure in the birth canal during delivery. The rest is absorbed by the body through the lymphatic and blood vessels during the first breaths.

Sometimes, however, this process takes a bit longer – the fluid partially remains in the lungs, and the baby has to breathe faster to take in enough oxygen.

Who is particularly affected?

  • Babies born by planned cesarean section (because the pressure of the birth canal is absent)
  • Babies who are born very quickly (precipitous delivery)
  • Babies of mothers with diabetes during pregnancy

How do you recognize it?

  • The baby breathes noticeably fast – often over 60 breaths per minute (normal is about 30 to 50).
  • The nostrils flare visibly with each breath (nasal flaring).
  • Sometimes you can hear a soft moaning or "grunting" during exhalation.
  • The skin may appear slightly bluish, especially on the lips and fingernails.

The good news: In most cases, transient tachypnea improves on its own within 24 to 72 hours. The baby is monitored in the hospital and receives supplemental oxygen if needed. Serious treatment is rarely necessary.

Surfactant Deficiency – When the Air Sacs Collapse

What happens?

Surfactant is a type of protective film that lines the tiny air sacs from the inside. You can think of it like dish soap that prevents soap bubbles from immediately collapsing. Without this film, the air sacs stick together when the baby exhales and can no longer open properly with the next breath. The baby then has to use an extreme amount of energy with every breath – a condition that can quickly become life-threatening.

Medically, this condition is known as Respiratory Distress Syndrome of the premature infant, or RDS (Respiratory Distress Syndrome).

Who is particularly affected?

  • Premature babies, especially those born before the 34th week of pregnancy – the more premature, the higher the risk
  • Babies of mothers with diabetes
  • Multiples (twins, triplets, etc.)
  • Babies who experienced oxygen deprivation during birth

A baby's body only begins producing surfactant around the 24th week of pregnancy, and there usually isn't enough of it until around the 35th week. A baby born significantly early therefore simply doesn't have enough of this vital substance.

How do you recognize it?

The symptoms are similar to transient tachypnea but are often more severe and worsen during the first hours after birth, rather than improving:

  • Rapid, labored breathing
  • Visible retractions of the skin between the ribs, below the breastbone, and above the collarbones with each breath (this shows how hard the baby is working)
  • Grunting or moaning during exhalation
  • Bluish discoloration of the skin (cyanosis)
  • Increasing exhaustion – the baby becomes floppy and less responsive

How is it treated?

In the hospital, surfactant can be administered directly into the baby's lungs – a treatment that is considered one of the great advances in neonatal medicine. Additionally, the baby receives breathing support, either through gentle positive pressure ventilation (CPAP – a mask that maintains slight air pressure to keep the air sacs open) or, in severe cases, through mechanical ventilation.

Meconium Aspiration – When the Baby's First Stool Gets Into the Lungs

What happens?

Meconium is the newborn's first stool – a dark green to black, sticky substance that accumulates in the baby's intestines during pregnancy. Normally, meconium is only passed after birth. Sometimes – especially during stress during delivery, post-term pregnancy (when the baby stays in the womb longer than expected), or oxygen deprivation – the baby passes this meconium into the amniotic fluid while still in the womb.

If the baby then inhales the contaminated amniotic fluid before or during birth, the thick meconium enters the airways and lungs. There it can:

  • Partially or completely block airways
  • Trigger inflammation in the lungs
  • Damage and inactivate surfactant
  • Lead to uneven ventilation of the lungs (some areas get too much air, others too little)

Who is particularly affected?

  • Post-term babies (after the 41st week of pregnancy)
  • Babies who experienced oxygen deprivation during birth
  • Underweight babies with restricted growth

How do you recognize it?

  • The amniotic fluid is greenish in color (noticed by the midwife or medical team)
  • The baby may have greenish-stained skin, nails, or umbilical cord
  • Severe respiratory distress immediately after birth
  • A distended chest
  • Significantly reduced alertness

How is it treated?

In the hospital, if the baby is limp after birth and not breathing vigorously, it is immediately suctioned and ventilated if necessary. In severe cases, intensive care in a neonatal intensive care unit may be required. Unlike previous recommendations, routine suctioning is no longer performed on a vigorously crying baby with green amniotic fluid, as this can cause more harm than good.

Recognizing Warning Signs: When You Must Act Immediately

Even after an initially uneventful birth, respiratory distress can develop in the first hours and days. As a parent or caregiver, you should watch for the following warning signs:

  • Rapid breathing: More than 60 breaths per minute over an extended period. You can count this by counting breaths for 15 seconds and multiplying by four.
  • Nasal flaring: The nostrils visibly move in and out with each breath.
  • Retractions: The skin visibly pulls in between the ribs, below the breastbone, or at the neck with each breath – the baby is visibly working hard to get air.
  • Moaning or grunting: An audible sound during exhalation, sometimes like a soft groaning.
  • Bluish discoloration: Especially on the lips, tongue, fingernails, or around the mouth. Note: Bluish hands and feet alone (acrocyanosis) are often normal in the first hours after birth.
  • Breathing pauses: The baby stops breathing for more than 20 seconds or becomes limp and pale during these pauses.
  • Poor feeding: The baby is too exhausted to feed or chokes noticeably often.
  • Unusual floppiness: The baby seems unusually sleepy, responds little to voice or touch.

Important: If you notice one or more of these signs, don't hesitate. Call emergency services immediately (emergency number 144 in Austria, 112 across Europe) or – if you're still in the hospital – press the emergency call button or call out loudly for nursing staff.

Initial Measures: What You Can Do Until Help Arrives

If a newborn shows obvious signs of respiratory distress and you're not in the hospital (such as during a home birth or after discharge), the following steps are crucial:

Step 1: Stay Calm and Call Emergency Services

As difficult as it is – panic won't help your baby. Call emergency services immediately (144 or 112) and calmly describe what you're observing. Stay on the phone – the dispatch center can guide you.

Step 2: Keep the Airway Clear

  • Place the baby on its back on a firm, flat surface.
  • Position the head in a neutral position – neither overextended nor bent forward. For a newborn, a slight extension is sufficient. A small rolled-up towel under the shoulders can help keep the airway open.
  • Carefully remove any visible obstructions from the mouth area (e.g., vomit), but never blindly insert a finger deep into the throat.

Step 3: Stimulation

Sometimes gentle stimulation is enough to encourage the baby to breathe more deeply:

  • Rub the baby's back gently but firmly with a towel.
  • Stroke or gently tap the soles of the feet.
  • Dry the baby off if it's still wet – this stimulates breathing and prevents cooling at the same time.

Step 4: Maintain Warmth

Newborns lose heat extremely quickly, and hypothermia drastically worsens respiratory distress. Keep the baby warm:

  • Dry the baby thoroughly and wrap it in dry, warm cloths.
  • Place the baby on your bare chest (skin-to-skin contact) and cover both of you – this is one of the most effective methods to maintain body temperature.
  • Avoid drafts.

Step 5: If the Baby Stops Breathing – Begin Rescue Breathing

If the baby doesn't breathe despite stimulation or is gasping (so-called agonal breathing, which is not effective breathing), you must begin rescue breathing:

  1. Position the head in a neutral position (slight extension).
  2. Give five initial rescue breaths: Cover the baby's mouth and nose simultaneously with your mouth. Blow gently – only the air in your cheeks, not your full lungs – into the airways. Each breath should last about one second. Watch to see if the chest rises.
  3. If the chest doesn't rise: Check the head position, the seal of your mouth, and try again.
  4. Check for pulse and signs of life: If the baby shows no signs of life after the five rescue breaths (no movement, no breathing, no response), begin chest compressions.
  5. Chest compressions for a newborn: Place two fingers (or both thumbs if you're encircling the baby's chest with both hands) on the lower half of the breastbone. Compress to about one-third of the chest depth – for a newborn, that's approximately 1.5 to 2 centimeters. The ratio is 3 chest compressions to 1 rescue breath (different for newborns than for older children or adults).
  6. Do not stop until professional help arrives or the baby starts breathing on its own again.

How to Tell the Three Causes Apart

For non-medical people, an exact diagnosis is of course not possible – and it's not necessary either. The initial measures are the same for all forms of respiratory distress. Still, it can help to have a rough picture:

Feature Transient Tachypnea Surfactant Deficiency Meconium Aspiration
Typical baby Full-term baby, often cesarean section Premature baby Post-term baby
Onset Immediately after birth First hours, gets worse Immediately after birth
Course Improves within 1–3 days Worsens without treatment Can vary widely
Amniotic fluid Clear Clear Greenish discolored
Severity Usually mild Can be severe Can be severe

What You Should NOT Do

  • Don't wait and hope it gets better on its own when clear warning signs are present.
  • Don't hold the baby upright and shake it – that is dangerous and doesn't help.
  • Don't try to suction with a straw or similar object – this can injure the airways.
  • Don't put excessive amounts of liquid in the baby's mouth – a baby with respiratory distress can easily choke.

Prevention: Can You Prevent Respiratory Distress in Newborns?

Not all causes are preventable, but some risk factors can be influenced:

  • Regular prenatal check-ups during pregnancy help identify risks early.
  • If there's a risk of premature birth, doctors can give the mother certain medications (corticosteroids) before delivery to accelerate the baby's lung maturation.
  • Breastfeeding promotes the overall health of the newborn and supports adaptation after birth.
  • Maintaining warmth immediately after birth through skin-to-skin contact is one of the simplest and most effective measures.

Practical Training

Knowing the theory is an important first step – but in an emergency, practiced skills are what count. How do I position a newborn's head correctly? How much force do I need for rescue breathing and chest compressions? What does the correct compression depth feel like? These things can only truly be internalized through hands-on practice. In our Baby Resuscitation Course, you'll train on realistic practice manikins, practicing exactly the measures that can make the difference in an emergency – step by step, in small groups, and guided by experienced instructors. You don't need any medical background whatsoever. What you bring is what matters most: the willingness to be prepared for your child or a child in your care.


Want to practice this hands-on?

In our Baby-Reanimationskurs you practice this topic hands-on with high-tech simulators and experienced instructors.

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Netzwerk KindersimulationAmerican Heart Association · ERC Guidelines